Dorky kid Greg Gaines (played by the brilliant and unlikely named Thomas Mann) has severe issues with closeness (he calls his best friend a “co-worker”) and is instructed by his mother to befriend Rachel (Olivia Cooke), a girl recently diagnosed with cancer. Far from being an indie tear-jerker, though, “this isn't a touching romantic story”, as Greg's narration reminds us. This is not least to the quirky nature of the film and the third titular character Earl, Greg's closest co-worker, who acts as the moral glue between Greg and Rachel.

In addition to hilarious writing and amazing performances, the film is laced with pop-cultural references by way of the movies that Greg and his Earl shoot in their spare time – spoofy takes on cult movies with titles like Sockwork Orange. Moving without being melodramatic, Me and Earl and the Dying Girl is a charmingly off-kilter fish-out-of-water plot about making friends, dealing with death, and enjoying life best as one can.